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Polyglutamine-FA in food is hydrolyzed to monoglutamine-FA prior to being absorbed. FA is heat labile. Causes of deficiency include: insufficient intake, malabsorption in gastrointestinal diseases, increased requirements during pregnancy. Antiepileptic drugs (phenytoin, primidone, phenobarbital) may decrease FA absorption, presumably by inhibiting the formation of monoglutamine- FA.
The cause of death is nervous system damage and seizures. In humans DDT causes acute neurotoxicity only after absorption of very large amounts. DDT is chemically stable and degraded in the environment and body at extremely slow rates. As a highly lipophilic substance, it accumulates in fat tissues.Widespread use of DDT in pest control has led to its accumulation in food chains to alarming levels.


Should the diabetic condition fail to resolve, consideration should first be given to insulin replacement. Oral antidiabetics of the sulfonylurea type increase the sensitivity of B-cells towards glucose, enabling them to increase release of insulin. These drugs probably promote depolarization of the ?-cell membrane by closing off ATP-gated K+ channels.
Substances with a long half-life are preferable for long-term anxiolytic treatment (light green area) because they permit maintenance of steady plasma levels with single daily dosing. Midazolam enjoys use by the i. v. route in preanesthetic medication and anesthetic combination regimens. Benzodiazepine Dependence Prolonged regular use of benzodiazepines can lead to physical dependence.


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